In soft tissues approximation, where a mid absorption of the suture is required.

In cardiovascular surgery, neurosurgery, general surgery, ophthalmic surgery, plastic surgery, skin surgery, thoracic surgery, when it is necessary to suture slow healing tissues or tissues suturing infected or contaminated tissues requiring a non absorbable suture. 

In soft tissues approximation and/or when a long – term absorption surgical suture is required

In general surgery, skin surgery, vascular surgery, plastic surgery, gastrointestinal surgery, when it is necessary to suture or to tie tissues requiring a non-absorbable suture; virgin silk is particularly indicated for ophthalmic surgery.

In general surgery, thoracic surgery, orthopaedics, gynaecology, ophtalmic surgery,neurosurgery, in soft tissues approximation, when it is necessary an absorbable surgical suture.

When it is necessary to suture slow healing tissues or tissues requiring a non absorbable suture.

 In general surgery, when it is necessary to suture or tie tissues requiring a non-absorbable suture, in cardiovascular surgery and orthopaedics

 In soft tissues approximation, where a fast absorption of the suture is required.For istance circumcisions, skin wounds and oral mucosa membrane.